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Search Result

Search Results for " tam receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T13074 TAM-IN-2 TAM Receptor
TAM-IN-2 is an inhibitor of TAM.
T7425 RU-301 TAM Receptor
RU-301 is a novel pan-tam inhibitor
T1968 UNC2250 TAM Receptor
UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).
T6982 SGI-7079 FLT , c-Met/HGFR , c-RET , TAM Receptor , Src
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance.
TQ0041 Ningetinib Tosylate VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T2311 LDC1267 TAM Receptor
LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).
T17205 UNC2541 Others , FLT , TAM Receptor
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
T2005 Dubermatinib TP0903 Apoptosis , TAM Receptor
Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.
T9123 DS-1205 TAM Receptor
DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro an...
T8327 ONO-7475 Trk receptor , TAM Receptor
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
T6907 NPS-1034 NPS1034,NPS 1034 Apoptosis , c-Met/HGFR , TAM Receptor
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
T2629 UNC2881 TAM Receptor
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.
TQ0021 Ningetinib CT-053,CT053PTSA VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T21302 UNC569 UNC 569 TAM Receptor
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...
T4426 CEP-40783 CEP 40783,RXDX-106 c-Met/HGFR , TAM Receptor
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).
T6269 Bemcentinib R428,BGB324 TAM Receptor
Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.
T2699 BMS 777607 BMS777607,BMS-777607,BMS 817378 c-Met/HGFR , TAM Receptor
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
T4409 Gilteritinib ASP2215 FLT , TAM Receptor , c-Kit
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an...
T9052 XL092 CL-092,JUN04542 VEGFR , c-Met/HGFR , TAM Receptor
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
T7379 2-D08 E1/E2/E3 Enzyme , TAM Receptor
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
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